E-AB-65060
IDH3A Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-65060
- Zusätzliche Namen:
- IDH3A
- Anwendung:
- IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human IDH3A (NP_005521.1).
- Uniprot:
- P50213
- Synonyme:
- H-IDH alpha;isocitrate dehydrogenase (NAD(+)) 3 alpha;isocitrate dehydrogenase (NAD+) alpha chain;isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial;isocitrate dehydrogenase 3 (NAD(+)) alpha;isocitrate dehydrogenase 3 (NAD+) alpha;isocitric dehydrogenase subunit alpha;NAD(+)-specific ICDH subunit alpha;NAD(H)-specific isocitrate dehydrogenase alpha subunit;NAD+-specific ICDH;RP90
- Weitere Details:
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
- Versandbedingungen:
- Blue Ice