UBE2D3 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-65057
Zusätzliche Namen:: E2(17)KB3,UBC4/5,UBCH5C,UBE2D3
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human UBE2D3 (NP_003331.1).
Uniprot:: P61077
Synonyme:: (E3-independent) E2 ubiquitin-conjugating enzyme D3;E2 ubiquitin-conjugating enzyme D3;E2(17)KB3;UBC4/5;UBCH5C;ubiquitin carrier protein D3;ubiquitin conjugating enzyme E2D 3;ubiquitin-conjugating enzyme E2 D3;ubiquitin-conjugating enzyme E2-17 kDa 3;ubiquitin-conjugating enzyme E2(17)KB 3;ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5);ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast);ubiquitin-protein ligase D3
Weitere Details:: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.