VPS26A Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-64967
Zusätzliche Namen:: HB58,Hbeta58,PEP8A,VPS26,VPS26A
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human VPS26A (NP_004887.2).
Uniprot:: O75436
Synonyme:: HB58;Hbeta58;PEP8A;vacuolar protein sorting 26 homolog A;vacuolar protein sorting-associated protein 26A;vesicle protein sorting 26A;VPS26;VPS26 retromer complex comonent A
Weitere Details:: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.