E-AB-64947
SLC6A4 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-64947
- Zusätzliche Namen:
- 5-HTT,5-HTTLPR,5HTT,HTT,OCD1,SERT,SERT1,SLC6A4,hSERT
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human SLC6A4 (NP_001036.1).
- Uniprot:
- P31645
- Synonyme:
- 5-HTT;5-HTTLPR;5-hydroxytryptamine (serotonin) transporter;5HT transporter;5HTT;hSERT;HTT;Na+/Cl- dependent serotonin transporter;OCD1;serotonin transporter 1;SERT;SERT1;sodium-dependent serotonin transporter;solute carrier family 6 (neurotransmitter transporter, serotonin), member 4;solute carrier family 6 (neurotransmitter transporter), member 4;Solute carrier family 6 member 4
- Weitere Details:
- This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
- Versandbedingungen:
- Blue Ice