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E-AB-64803

MDFI Polyclonal Antibody

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£195.30

War £217.00

SKU:
E-AB-64803
Zusätzliche Namen:
I-MF,I-mfa,MDFI
Anwendung:
WB
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human MDFI (NP_005577.1).
Uniprot:
Q99750
Synonyme:
I-MF;I-mfa;inhibitor of MyoD family a;myoD family inhibitor;myogenic repressor I-mf
Weitere Details:
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Versandbedingungen:
Blue Ice