GEMIN8 Polyclonal Antibody

Größe

£195.30

War £217.00

SKU:: E-AB-64802
Zusätzliche Namen:: FAM51A1,GEMIN8
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human GEMIN8 (NP_060326.1).
Uniprot:: Q9NWZ8
Synonyme:: FAM51A1;family with sequence similarity 51, member A1;gem-associated protein 8;gemin-8;Protein FAM51A1
Weitere Details:: The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.