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E-AB-64726

PICK1 Polyclonal Antibody

Größe

£195.30

War £217.00

SKU:
E-AB-64726
Zusätzliche Namen:
PICK,PICK1,PRKCABP
Anwendung:
IHC
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human PICK1
Uniprot:
Q9NRD5
Synonyme:
PICK;PRKCA-binding protein;PRKCABP;protein interacting with C kinase 1;protein kinase C-alpha-binding protein
Weitere Details:
The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
Versandbedingungen:
Blue Ice