E-AB-64653
ALAS1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-64653
- Zusätzliche Namen:
- ALAS,ALAS-H,ALAS1,ALAS3,ALASH,MIG4
- Anwendung:
- IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ALAS1 (NP_954635.1).
- Uniprot:
- P13196
- Synonyme:
- 5-aminolevulinate synthase, nonspecific, mitochondrial;5-aminolevulinic acid synthase 1;ALAS;ALAS-H;ALAS3;ALASH;aminolevulinate, delta-, synthase 1;delta-ALA synthase 1;delta-aminolevulinate synthase 1;MIG4;migration-inducing protein 4
- Weitere Details:
- This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Versandbedingungen:
- Blue Ice