TBCB Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-64516
Zusätzliche Namen:: CG22,CKAP1,CKAPI,TBCB
Anwendung:: IHC
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human TBCB (NP_001272.2).
Uniprot:: Q99426
Synonyme:: CG22;CKAP1;CKAPI;cytoskeleton associated protein 1;Cytoskeleton-associated protein 1;cytoskeleton-associated protein CKAPI;tubulin-folding cofactor B;tubulin-specific chaperone B
Weitere Details:: Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of A Alpha/B Beta Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), B (TBCB), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCB (tubulin folding cofactor B), also known as CG22, CKAP1 or CKAPI, is a 244 amino acid cytoplasmic protein containing one CAP-Gly domain and in widely expressed. TBCB is involved in the regulation of tubulin heterodimer dissociation and may function as a negative regulator of axonal growth.