E-AB-64476
UNC13D Polyclonal Antibody
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£195.30
War £217.00
- SKU:
- E-AB-64476
- Zusätzliche Namen:
- FHL3,HLH3,HPLH3,Munc13-4,UNC13D
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human UNC13D (NP_954712.1).
- Uniprot:
- Q70J99
- Synonyme:
- FHL3;HLH3;HPLH3;Munc13-4;protein unc-13 homolog D
- Weitere Details:
- This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
- Versandbedingungen:
- Blue Ice