SORL1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-64429
Zusätzliche Namen:: C11orf32,LR11,LRP9,SORL1,SORLA,SorLA-1,gp250
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SORL1 (NP_003096.1).
Uniprot:: Q92673
Synonyme:: C11orf32;gp250;LDLR relative with 11 ligand-binding repeats;low-density lipoprotein receptor relative with 11 ligand-binding repeats;LR11;LRP9;mosaic protein LR11;SORLA;SorLA-1;sortilin-related receptor;sortilin-related receptor, L(DLR class) A repeats containing;sorting protein-related receptor containing LDLR class A repeats
Weitere Details:: This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease.