E-AB-64359
ATP23 Polyclonal Antibody
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£195.30
War £217.00
- SKU:
- E-AB-64359
- Zusätzliche Namen:
- ATP23,KUB3,XRCC6BP1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ATP23 (NP_150592.1).
- Uniprot:
- Q9Y6H3
- Synonyme:
- Ku70-binding protein 3;KUB3;mitochondrial inner membrane protease ATP23 homolog;XRCC6-binding protein 1;XRCC6BP1
- Weitere Details:
- The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice