E-AB-64237
HDAC3 Polyclonal Antibody
Größe
£211.50
War £235.00
- SKU:
- E-AB-64237
- Zusätzliche Namen:
- HD3,HDAC3,RPD3,RPD3-2
- Anwendung:
- IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human HDAC3 (NP_003874.2).
- Uniprot:
- O15379
- Synonyme:
- HD3;histone deacetylase 3;KDAC3;RPD3;RPD3-2;SMAP45
- Weitere Details:
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
- Versandbedingungen:
- Blue Ice