CAPN3 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-64116
Zusätzliche Namen:: CANP3,CANPL3,CAPN3,LGMD2,LGMD2A,calpain-3,nCL-1,p94
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human CAPN3 (NP_775111.1).
Uniprot:: P20807
Synonyme:: Calcium-activated neutral proteinase 3;Calpain L3;Calpain p94;calpain p94, large [catalytic] subunit;calpain-3;calpain, large polypeptide L3;CANP3;CANPL3;LGMD2;LGMD2A;LGMDD4;LGMDR1;Muscle-specific calcium-activated neutral protease 3;muscle-specific calcium-activated neutral protease 3 large subunit;nCL-1;new calpain 1;p94
Weitere Details:: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.