VDAC3 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-64061
Zusätzliche Namen:: HD-VDAC3,VDAC-3,VDAC3
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human VDAC3 (NP_005653.3).
Uniprot:: Q9Y277
Synonyme:: HD-VDAC3;outer mitochondrial membrane protein porin 3;VDAC-3;voltage-dependent anion-selective channel protein 3
Weitere Details:: This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.