E-AB-64012
XRCC1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-64012
- Zusätzliche Namen:
- RCC,XRCC1
- Anwendung:
- IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human XRCC1 (NP_006288.2).
- Uniprot:
- P18887
- Synonyme:
- DNA repair protein XRCC1;RCC;SCAR26;X-ray repair complementing defective repair in Chinese hamster cells 1;X-ray repair cross-complementing protein 1
- Weitere Details:
- The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
- Versandbedingungen:
- Blue Ice