E-AB-63925
GPM6A Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-63925
- Zusätzliche Namen:
- GPM6,GPM6A,M6A
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human GPM6A (NP_005268.1).
- Uniprot:
- P51674
- Synonyme:
- GPM6;M6A;neuronal membrane glycoprotein M6-a
- Weitere Details:
- Neuronal membrane glycoprotein M6-ais aproteinthat in humans is encoded by theGPM6Agene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs), enhances internalization and recycling of mu-type opioid receptor.
- Versandbedingungen:
- Blue Ice