E-AB-63880
MARK1 Polyclonal Antibody
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£195.30
War £217.00
- SKU:
- E-AB-63880
- Zusätzliche Namen:
- MARK,MARK1,Par-1c,Par1c
- Anwendung:
- IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MARK1 (NP_061120.3).
- Uniprot:
- Q9P0L2
- Synonyme:
- MAP/microtubule affinity-regulating kinase 1;MARK;Par-1c;PAR1 homolog c;Par1c;serine/threonine-protein kinase MARK1
- Weitere Details:
- MAP/microtubule affinity-regulating kinase 1 (MARK1) is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart.
- Versandbedingungen:
- Blue Ice