E-AB-63794
KIFAP3 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-63794
- Zusätzliche Namen:
- FLA3,KAP-1,KAP-3,KAP3,KIFAP3,SMAP,Smg-GDS,dJ190I16.1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human KIFAP3 (NP_055785.2).
- Uniprot:
- Q92845
- Synonyme:
- dJ190I16.1;FLA3;KAP-1;KAP-3;KAP3;kinesin-associated protein 3;small G protein GDP dissociation stimulator;SMAP;smg GDS-associated protein;Smg-GDS
- Weitere Details:
- The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice