E-AB-63718
CHD3 Polyclonal Antibody
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£195.30
War £217.00
- SKU:
- E-AB-63718
- Zusätzliche Namen:
- CHD3,Mi-2a,Mi2-ALPHA,ZFH
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human CHD3 (NP_001005273.1).
- Uniprot:
- Q12873
- Synonyme:
- ATP-dependent helicase CHD3;CHD-3;chromodomain-helicase-DNA-binding protein 3;hZFH;mi-2 autoantigen 240 kDa protein;Mi-2a;Mi2-ALPHA;SNIBCPS;ZFH;zinc finger helicase;zinc-finger helicase (Snf2-like)
- Weitere Details:
- This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
- Versandbedingungen:
- Blue Ice