E-AB-63687
MYBPC3 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-63687
- Zusätzliche Namen:
- CMD1MM,CMH4,FHC,LVNC10,MYBP-C,MYBPC3,cardiac
- Anwendung:
- IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MYBPC3 (NP_000247.2).
- Uniprot:
- Q14896
- Synonyme:
- C-protein, cardiac muscle isoform;CMD1MM;CMH4;cMyBP-C;FHC;LVNC10;MYBP-C;myosin binding protein C, cardiac;myosin-binding protein C, cardiac-type;truncated cardiac myosin-binding protein C
- Weitere Details:
- MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
- Versandbedingungen:
- Blue Ice