E-AB-63554
CHD4 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-63554
- Zusätzliche Namen:
- CHD-4,CHD4,Mi-2b,Mi2-BETA,SIHIWES
- Anwendung:
- IHC, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human CHD4 (NP_001264.2).
- Uniprot:
- Q14839
- Synonyme:
- ATP-dependent helicase CHD4;CHD-4;chromodomain-helicase-DNA-binding protein 4;Mi-2 autoantigen 218 kDa protein;Mi-2b;Mi2-BETA;SIHIWES
- Weitere Details:
- The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Versandbedingungen:
- Blue Ice