E-AB-62876
(KO Validated) POR Polyclonal Antibody
Größe
£210.60
War £234.00
- SKU:
- E-AB-62876
- Zusätzliche Namen:
- CPR,CYPOR,P450R,POR
- Anwendung:
- IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human POR (NP_000932.3).
- Uniprot:
- P16435
- Synonyme:
- CPR;CYPOR;NADPH--cytochrome P450 reductase;NADPH--hemoprotein reductase;NADPH-dependent cytochrome P450 reductase;P450 (cytochrome) oxidoreductase;P450R
- Weitere Details:
- This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
- Versandbedingungen:
- Blue Ice