E-AB-62775
GRIA4 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-62775
- Zusätzliche Namen:
- GLUR4,GLUR4C,GLURD,GRIA4,GluA4
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human GRIA4 (NP_001070712.1).
- Uniprot:
- P48058
- Synonyme:
- AMPA-selective glutamate receptor 4;GluA4;GluA4-ATD;gluR-4;gluR-D;GLUR4;GLUR4C;GLURD;glutamate receptor 4;Glutamate receptor ionotropic, AMPA 4;glutamate receptor, ionotrophic, AMPA 4;glutamate receptor, ionotropic, AMPA 4;NEDSGA
- Weitere Details:
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
- Versandbedingungen:
- Blue Ice