E-AB-62761
GLDC Polyclonal Antibody
Größe
£211.50
War £235.00
- SKU:
- E-AB-62761
- Zusätzliche Namen:
- GCE,GCSP,GLDC,HYGN1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human GLDC (NP_000161.2).
- Uniprot:
- P23378
- Synonyme:
- GCE;GCSP;Glycine cleavage system P protein;glycine cleavage system protein P;Glycine decarboxylase;glycine decarboxylase P-protein;glycine dehydrogenase (aminomethyl-transferring);glycine dehydrogenase (decarboxylating), mitochondrial;glycine dehydrogenase [decarboxylating], mitochondrial;HYGN1;nonketotic hyperglycinemia
- Weitere Details:
- Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
- Versandbedingungen:
- Blue Ice