E-AB-62754
GBA Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-62754
- Zusätzliche Namen:
- GBA,GBA1,GCB,GLUC
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human GBA (NP_000148.2).
- Uniprot:
- P04062
- Synonyme:
- acid beta-glucosidase;alglucerase;beta-GC;beta-glucocerebrosidase;cholesterol glucosyltransferase;cholesteryl-beta-glucosidase;D-glucosyl-N-acylsphingosine glucohydrolase;GBA1;GCB;GLUC;glucocerebrosidase;glucosidase, beta, acid;glucosylceramidase-like protein;imiglucerase;lysosomal acid GCase;lysosomal acid glucosylceramidase;lysosomal glucocerebrosidase;SGTase
- Weitere Details:
- This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice