FLNB Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-62747
Zusätzliche Namen:: ABP-278,ABP-280,AOI,FH1,FLN-B,FLN1L,FLNB,LRS1,SCT,TABP,TAP,filamin-B
Anwendung:: IHC, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human FLNB (NP_001157789.1).
Uniprot:: O75369
Synonyme:: ABP-278;ABP-280;ABP-280 homolog;actin binding protein 278;actin-binding-like protein;AOI;beta-filamin;FH1;filamin B, beta;filamin homolog 1;filamin-3;filamin-B;FLN-B;FLN1L;Larsen syndrome 1 (autosomal dominant);LRS1;SCT;TABP;TAP;thyroid autoantigen;Truncated actin-binding protein
Weitere Details:: This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.