ELAVL3 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-62727
Zusätzliche Namen:: ELAVL3,HUC,HUCL,PLE21
Anwendung:: IHC, WB, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human ELAVL3 (NP_001411.2).
Uniprot:: Q14576
Synonyme:: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C);ELAV like neuron-specific RNA binding protein 3;ELAV-like protein 3;Hu antigen C;hu-antigen C;HUC;HUCL;paraneoplastic cerebellar degeneration-associated antigen;paraneoplastic limbic encephalitis antigen 21;PLE21
Weitere Details:: A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.