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E-AB-62608

ACOX1 Polyclonal Antibody

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£195.30

War £217.00

SKU:
E-AB-62608
Zusätzliche Namen:
ACOX,ACOX1,PALMCOX,SCOX
Anwendung:
IHC, IF
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human ACOX1 (NP_004026.2).
Uniprot:
Q15067
Synonyme:
ACOX;acyl-CoA oxidase 1, palmitoyl;acyl-CoA oxidase, straight-chain;acyl-Coenzyme A oxidase 1, palmitoyl;AOX;MITCH;PALMCOX;palmitoyl-CoA oxidase;peroxisomal acyl-coenzyme A oxidase 1;peroxisomal fatty acyl-CoA oxidase;SCOX;straight-chain acyl-CoA oxidase
Weitere Details:
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
Versandbedingungen:
Blue Ice