E-AB-62500
MKL1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-62500
- Zusätzliche Namen:
- BSAC,MAL,MKL1,MRTF-A
- Anwendung:
- IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MKL1 (NP_065882.1).
- Uniprot:
- Q969V6
- Synonyme:
- basic, SAP and coiled-coil domain;BSAC;MAL;megakaryoblastic leukemia (translocation) 1;megakaryoblastic leukemia 1 protein;megakaryocytic acute leukemia protein;MKL;MKL/myocardin-like protein 1;MKL1;MRTF-A;myocardin-related transcription factor A
- Weitere Details:
- The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice