NSL1 Polyclonal Antibody

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SKU:: E-AB-62407
Zusätzliche Namen:: C1orf48,DC8,MIS14,NSL1
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human NSL1 (NP_056286.3).
Uniprot:: Q96IY1
Synonyme:: C1orf48;DC8;kinetochore-associated protein NSL1 homolog;MIS14;NSL1, MIND kinetochore complex component, homolog;NSL1, MIS12 kinetochore complex component
Weitere Details:: This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X.