KDM4A Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-62318
Zusätzliche Namen:: JHDM3A,JMJD2,JMJD2A,KDM4A,TDRD14A
Anwendung:: IHC
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human KDM4A (NP_055478.2).
Uniprot:: O75164
Synonyme:: [histone H3]-trimethyl-L-lysine(36) demethylase 4A;[histone H3]-trimethyl-L-lysine(9) demethylase 4A;JHDM3A;jmjC domain-containing histone demethylation protein 3A;JMJD2;JMJD2A;jumonji C domain-containing histone demethylase 3A;jumonji domain containing 2;jumonji domain containing 2A;jumonji domain-containing protein 2A;lysine (K)-specific demethylase 4A;lysine-specific demethylase 4A;TDRD14A;tudor domain containing 14A
Weitere Details:: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.