EIF5B Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-62317
Zusätzliche Namen:: EIF5B,IF2
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human EIF5B (NP_056988.3).
Uniprot:: O60841
Synonyme:: eIF-5B;eukaryotic translation initiation factor 5B;IF2;translation initiation factor IF-2;translation initiation factor IF2
Weitere Details:: Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.