AURKC Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-62229
Zusätzliche Namen:: AIE2,AIK3,ARK3,AURKC,AurC,HEL-S-90,SPGF5,STK13,aurora-C
Anwendung:: IHC, WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human AURKC
Uniprot:: Q9UQB9
Synonyme:: AIE2;AIK3;ARK-3;ARK3;AurC;aurora 3;aurora kinase C;aurora-C;aurora-related kinase 3;aurora/IPL1-related kinase 3;aurora/IPL1/EG2 protein 2;epididymis secretory protein Li 90;HEL-S-90;serine/threonine kinase 13 (aurora/IPL1-like);serine/threonine-protein kinase 13;serine/threonine-protein kinase aurora-C;SPGF5;STK13
Weitere Details:: This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.