(KO Validated) STK4 Polyclonal Antibody

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£210.60

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SKU:: E-AB-62228
Zusätzliche Namen:: KRS2,MST1,STK4,YSK3
Anwendung:: IHC, WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human STK4 (NP_006273.1).
Uniprot:: Q13043
Synonyme:: hippo homolog;kinase responsive to stress 2;KRS2;mammalian STE20-like protein kinase 1;mammalian sterile 20-like 1;MST1;serine/threonine-protein kinase 4;serine/threonine-protein kinase Krs-2;STE20-like kinase MST1;YSK3
Weitere Details:: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.