E-AB-62147
NEDD4 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-62147
- Zusätzliche Namen:
- NEDD4,NEDD4-1,RPF1
- Anwendung:
- IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human NEDD4 (NP_940682.2).
- Uniprot:
- P46934
- Synonyme:
- cell proliferation-inducing gene 53 protein;E3 ubiquitin-protein ligase NEDD4;HECT-type E3 ubiquitin transferase NEDD4;NEDD4-1;Neural precursor cell expressed developmentally down-regulated protein 4;neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase;receptor-potentiating factor 1;RPF1
- Weitere Details:
- This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
- Versandbedingungen:
- Blue Ice