E-AB-62037
CFL2 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-62037
- Zusätzliche Namen:
- CFL2,NEM7,cofilin-2
- Anwendung:
- WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human CFL2 (NP_068733.1).
- Uniprot:
- Q9Y281
- Synonyme:
- cofilin 2 (muscle);cofilin-2;Cofilin, muscle isoform;NEM7;nemaline myopathy type 7
- Weitere Details:
- This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice