GRP Polyclonal Antibody

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£195.30

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SKU:: E-AB-61920
Zusätzliche Namen:: BN,GRP,GRP ,GRP-10,preproGRP,proGRP
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human GRP (NP_002082.2).
Uniprot:: P07492
Synonyme:: BN;bombesin;gastrin-releasing peptide;GRP-10;neuromedin C;pre-progastrin releasing peptide;prepro-GRP;preproGRP;proGRP;testicular tissue protein Li 103
Weitere Details:: This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.