E-AB-61902
RHOH Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-61902
- Zusätzliche Namen:
- ARHH,RHOH,TTF
- Anwendung:
- WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human RHOH (NP_004301.1).
- Uniprot:
- Q15669
- Synonyme:
- ARHH;GTP-binding protein TTF;ras homolog gene family, member H;rho-related GTP-binding protein RhoH;Translocation three four protein;TTF;TTF, translocation three four
- Weitere Details:
- The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.
- Versandbedingungen:
- Blue Ice