E-AB-61854
DNTT Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-61854
- Zusätzliche Namen:
- DNTT,TDT
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human DNTT (NP_004079.3).
- Uniprot:
- P04053
- Synonyme:
- DNA nucleotidylexotransferase;nucleosidetriphosphate:DNA deoxynucleotidylexotransferase;TDT;terminal addition enzyme;terminal deoxynucleotidyltransferase;terminal deoxyribonucleotidyltransferase;terminal transferase
- Weitere Details:
- This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
- Versandbedingungen:
- Blue Ice