E-AB-61675
ZAK Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-61675
- Zusätzliche Namen:
- AZK,MAP3K20,MLK7,MLT,MLTK,MLTKalpha,MLTKbeta,MRK,SFMMP,ZAK,mlklak,pk
- Anwendung:
- IHC, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ZAK (NP_598407.1).
- Uniprot:
- Q9NYL2
- Synonyme:
- AZK;CNM6;HCCS-4;human cervical cancer suppressor gene 4 protein;Leucine zipper- and sterile alpha motif-containing kinase;mitogen-activated protein kinase kinase kinase 20;mitogen-activated protein kinase kinase kinase MLT;mixed lineage kinase 7;mixed lineage kinase with a leucine zipper and a sterile alpha motif;Mixed lineage kinase-related kinase;mixed lineage kinase-related kinase MRK-beta;MLK-like mitogen-activated protein triple kinase;MLK7;mlklak;MLT;MLTK;MLTKalpha;MLTKbeta;MRK;pk;SFMMP;sterile alpha motif and leucine zipper containing kinase AZK;Sterile alpha motif- and leucine zipper-containing kinase AZK;ZAK;ZAK1 homolog, leucine zipper and sterile-alpha motif kinase
- Weitere Details:
- This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Versandbedingungen:
- Blue Ice