PTGS1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-61656
Zusätzliche Namen:: COX1,COX3,PCOX1,PES-1,PGG/HS,PGHS-1,PGHS1,PHS1,PTGHS,PTGS1
Anwendung:: IHC, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human PTGS1 (NP_001258094.1).
Uniprot:: P23219
Synonyme:: COX1;COX3;cyclooxygenase-1;PCOX1;PES-1;PGG/HS;PGH synthase 1;PGHS-1;PGHS1;PHS1;prostaglandin G/H synthase 1;prostaglandin H2 synthase 1;Prostaglandin-endoperoxide synthase 1;prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase);PTGHS
Weitere Details:: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.