E-AB-61653
PAX6 Polyclonal Antibody
Größe
£211.50
War £235.00
- SKU:
- E-AB-61653
- Zusätzliche Namen:
- AN,AN2,ASGD5,D11S812E,FVH1,MGDA,PAX6,WAGR
- Anwendung:
- IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PAX6 (NP_000271.1).
- Uniprot:
- P26367
- Synonyme:
- AN;AN1;AN2;Aniridia 1;Aniridia 2;aniridia type II protein;ASGD5;D11S812E;FVH1;MGDA;oculorhombin;paired box homeotic gene-6;paired box protein Pax-6;WAGR
- Weitere Details:
- This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.
- Versandbedingungen:
- Blue Ice