PARP3 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-61629
Zusätzliche Namen:: ADPRT3,ADPRTL2,ADPRTL3,ARTD3,IRT1,PADPRT-3,PARP3
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human PARP3 (NP_001003931.3).
Uniprot:: Q9Y6F1
Synonyme:: ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 2;ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3;ADP-ribosyltransferase diphtheria toxin-like 3;ADPRT-3;ADPRT3;ADPRTL2;ADPRTL3;ARTD3;DNA ADP-ribosyltransferase PARP3;IRT1;NAD(+) ADP-ribosyltransferase 3;NAD+ ADP-ribosyltransferase 3;PADPRT-3;poly [ADP-ribose] polymerase 3;poly(ADP-ribose) synthetase-3;poly[ADP-ribose] synthase 3;poly[ADP-ribose] synthetase 3;protein mono-ADP-ribosyltransferase PARP3
Weitere Details:: The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.