ELF5 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-61568
Zusätzliche Namen:: ELF5,ESE2
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human ELF5 (NP_001413.1).
Uniprot:: Q9UKW6
Synonyme:: E74-like factor 5;E74-like factor 5 (ets domain transcription factor);epithelium-restricted ESE-1-related Ets factor;epithelium-specific Ets transcription factor 2;ESE2;ETS-related transcription factor Elf-5
Weitere Details:: The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.