CSRNP1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-61545
Zusätzliche Namen:: AXUD1,CSRNP-1,CSRNP1,FAM130B,TAIP-3,URAX1
Anwendung:: IHC, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human CSRNP1 (NP_149016.2).
Uniprot:: Q96S65
Synonyme:: axin-1 up-regulated gene 1 protein;AXIN1 up-regulated 1;AXUD1;CSRNP-1;cysteine/serine-rich nuclear protein 1;FAM130B;Protein URAX1;TAIP-3;TGF-beta-induced apoptosis protein 3;URAX1
Weitere Details:: This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants.