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E-AB-61499

PIAS3 Polyclonal Antibody

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£195.30

War £217.00

SKU:
E-AB-61499
Zusätzliche Namen:
PIAS3,ZMIZ5
Anwendung:
IHC
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human PIAS3 (NP_006090.2).
Uniprot:
Q9Y6X2
Synonyme:
E3 SUMO-protein ligase PIAS3;E3 SUMO-protein transferase PIAS3;protein inhibitor of activated STAT protein 3;zinc finger, MIZ-type containing 5;ZMIZ5
Weitere Details:
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.
Versandbedingungen:
Blue Ice