E-AB-61454
TNNI3 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-61454
- Zusätzliche Namen:
- CMD1FF,CMD2A,CMH7,RCM1,TNNC1,TNNI3,cTnI,troponin I3
- Anwendung:
- WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human TNNI3 (NP_000354.4).
- Uniprot:
- P19429
- Synonyme:
- Cardiac troponin I;cardiomyopathy, dilated 2A (autosomal recessive);CMD1FF;CMD2A;CMH7;cTnI;RCM1;TNNC1;troponin I type 3 (cardiac);troponin I, cardiac muscle
- Weitere Details:
- Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
- Versandbedingungen:
- Blue Ice