SMARCB1 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-61106
Zusätzliche Namen:: BAF47,CSS3,INI1,MRD15,PPP1R144,RDT,RTPS1,SMARCB1,SNF5,SNF5L1,SWNTS1,Sfh1p,Snr1,hSNFS
Anwendung:: IHC
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SMARCB1 (NP_001007469.1).
Uniprot:: Q12824
Synonyme:: BAF47;BRG1-associated factor 47;CSS3;hSNF5;hSNFS;INI1;integrase interactor 1 protein;malignant rhabdoid tumor suppressor;MRD15;PPP1R144;protein phosphatase 1, regulatory subunit 144;RDT;RTPS1;Sfh1p;SNF5;SNF5 homolog;SNF5L1;Snr1;sucrose nonfermenting, yeast, homolog-like 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;SWI/SNF-related matrix-associated protein;SWNTS1
Weitere Details:: The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.