ROR2 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-61029
Zusätzliche Namen:: BDB,BDB1,NTRKR2,ROR2
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human ROR2 (NP_004551.2).
Uniprot:: Q01974
Synonyme:: BDB;BDB1;neurotrophic tyrosine kinase receptor-related 2;Neurotrophic tyrosine kinase, receptor-related 2;NTRKR2;tyrosine-protein kinase transmembrane receptor ROR2
Weitere Details:: The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.